Introduction to blood and Haematopoiesis (Blood physiology lecture material compilation) by Bond anyaehie, SI Okpala, Ugwu sandra, Nnali Nkechinyere, odoemena celevian PDF free download

Topics: Plasma, haemoglobin, blood clotting, heme, Blood, plasma proteins, Blood clotting mehanisms, hemoglobin, Blood clotting, Platelets, Blood clotting pathway, Blood clotting factors, Bleeding disorder, hemophilia, Hemoglobin, Porphyrin ring, haem

Topics: Hemostasis, Blood Component Therapy, Cellular Homeostasis, Cell Morphology, cell membrane, cytoplasm, nucleus, DNA duplication, DNA transcription, DNA translation, Gene expression, Protein Synthesis, Protein Processing, Ubiquitin System, Ubiquitin System, Apoptosis, cell cycle, Abnormal Tissue Homeostasis, cancer, Hematopoietic System, Hematopoietic Organs, Hematopoiesis, Hematopoietic Tissue, bone marrow, thymus, spleen, lymph nodes, Mucosa-Associated Lymphoid Tissue, Lymphadenopathy, Hematopoietic Precursor Cells, Growth Factor Function, cytokine, growth factor, Cytokine Receptors, Signaling Pathways, transcription Factors, Hematopoietic Growth Factors, Hematopoietic Microenvironment, Hemoglobin Structure, Hemoglobin, Hemoglobin Synthesis, heme, Globin Chain Synthesis, Embryonic Hemoglobins, Fetal Hemoglobin, Adult Hemoglobins, Glycosylated Hemoglobin, Hemoglobin Function, Oxygen Transport, Carbon Dioxide Transport, Artificial Oxygen Carriers, Hemoglobin Catabolism, Extravascular Destruction, Intravascular Destruction, Acquired Nonfunctional Hemoglobins, Methemoglobin, Sulfhemoglobin, Carboxyhemoglobin, Erythropoiesis, Red Blood Cell Maturation, Erythroid Progenitor Cells, Erythroid-Maturing Cells, cell maturation, Erythroblastic Islands, Erythrocyte, Erythrocyte Membrane, Membrane Permeability, Erythrocyte Metabolism, Glycolytic Pathway, Hexose Monophosphate shunt, Methemoglobin Reductase Pathway, Rapoport-Luebering Shunt, Erythrocyte Kinetics, Erythrocyte Concentration, Granulocyte, Monocyte, Leukocyte Surface Markers, Leukocyte Function, neutrophils, Eosinophils, Basophils, Lymphocyte Function, Lymphocyte Metabolism, aging, platelet, lymphocytes, complete blood count, peripheral blood smear evaluation, anaemia, Hemoglobinopathies, heme synthesis, megoblastic anaemia, Thalassemia, Hypoproliferative Anemia, Hemolytic Anemia, immune anemia, Lymphocyte Disorders, Myeloproliferative Neoplasms, Neoplastic Hematologic Disorders, Hematopoietic Neoplasms, Myelodysplastic Syndromes, Acute Myeloid Leukemia, Precursor Lymphoid Neoplasm, Bone Marrow, Thrombophilia

Topics: Antigens antibodies, Immune response, innate immunity, genetic immunity, acquired immunity, Naturally Acquired Active Immunity, Naturally Acquired Passive Immunity, Artificially Acquired Immunity, Artificially Acquired Passive Immunity, serum, antiserum, serology, gamma globulins, serum sickness, Humoral Immunity, Antibody-Mediated immunity, epitopes, Antibody Structure, Immunoglobulin Classes, clonal selection, Apoptosis, antibody binding, Immunological Memory, T Cells, cell mediated immunity, Cytotoxic T Cells, Destroy target cells, Cytotoxic T Cells Lyse Infected Cells, Delayed Hypersensitivity T Cells, T Suppressor Cells, Activated Macrophages, Stimulated phagocytes, Natural Killer Cells, Antibody Production, T-Dependent Antigens, Antibody Dependent Cell Mediated Cytotoxicity

Topics: Blood, Physiology, red blood cell morphology, red blood cell, Erythropoiesis, Poikilocytosis, Anisocytosis, Roleaux, Pluripotential haemopoietic stem cells, Colony Forming Unit erythrocyte, Erythropoietin, folic acid, iron, Pluripotential haemopoietic stem cells, Blood transfusion, anaemia, platelets, thrombocytes, white blood cell, Neutrophils, Cortisol hormone, eosinophils, Basophils, Lymphocytes, Monocyte, reticulocyte, myelopoiesis, Chemotaxis, Opsonization, Diapedesis, Phagocytosis, Leukaemia, Leukopenia, blood group, Rhesus factor, Agglutinin, blood fluid compartments, Agglutinin, intracellular fluid, Hyponatraemia, Hypernatraemia, Hypokalaemia, biological rhythm, Transmembrane protein, membrane transport, passive transport, active transport, haemoglobin level, haemoglobin disease, anemia, biological potentials, resting membrane potential, action potential, cell, osmolality, nerve impulse conduction, synaptic transmission, neuromuscular transmission, neurotransmitters

Topics: ankyrin complex, Antigens, Antibodies, H antigen, RBC Precursor Structure, B Antigen, A Antigen, Landsteiner’s Rule, Red blood cell antibodies, Cold antibodies, Warm antibodies, Rh blood group, Rh antigens, Rh antibodies, Lewis blood group, Lewis antibodies, Kell blood group, Kell antibodies

Topics: genome, Noncoding DNA, Histone Organization, Micro-RNA, Long Noncoding RNA, gene editing, CELLULAR HOUSEKEEPING, plasma membrane, Passive Membrane Diffusion, cytoskeleton, cell-cell interactions, biosynthetic machinery, waste disposal, cellular metabolism, mitochondrial function, cellular activation, cell signaling, signal transduction pathway, modular signaling proteins, transcription factors, extracellular matrix, Proliferation, Cell Cycle, stem cells, regenerative medicine, genetics, epigenetics, cell injury, cell death, reversible cell injury, necrosis, apoptosis, tissue necrosis, autophagy, hypoxia, ischemia, ischemia-reperfusion injury, oxidative stress, Endoplasmic Reticulum Stress, DNA damage, inflammation, Mitochondrial Dysfunction, Hypertrophy, hyperplasia, atrophy, metaplasia, intracellular accumulations, pathologic calcification, cellular aging, Chemotaxis of Leukocytes, MEDIATORS OF INFLAMMATION, Vasoactive Amines, Histamine, Serotonin, Arachidonic Acid Metabolites, Prostaglandins, Lipoxins, Leukotrienes, Cytokines, Chemokines, complement system, kinins, neuropeptides, serous inflammation, fibrinous inflammation, purulent inflammation, ulcer, chronic inflammation, Liver Regeneration, tissue repair, cell Regeneration, tissue Regeneration, Angiogenesis, Hyperemia, congestion, edema, Increased Hydrostatic Pressure, Reduced Plasma Osmotic Pressure, Lymphatic Obstruction, Sodium and Water Retention, hemorrhage, hemostasis, thrombosis, platelets, coagulation cascade, Endothelial Injury, Abnormal Blood Flow, Hypercoagulability, Venous Thrombosis, Phlebothrombosis, Disseminated Intravascular Coagulation, Pulmonary Thromboembolism, embolism, Systemic Thromboembolism, Fat Embolism, Amniotic Fluid Embolism, Air Embolism, infarction, shock, immune response, innate immunity, toll-loke receptors, adaptive immunity, T Lymphocytes, B Lymphocytes, Antigen-Presenting Cells, Dendritic Cells, Lymphoid Tissues, Peripheral Lymphoid Organs, cytokines, Cell-Mediated Immunity, Humoral Immunity, hypersensistivity, Antibody-Mediated Diseases, Immune Complex–Mediated Diseases, immune complex

Topics: Immune Hemolytic disorder, Auto-immune Hemolytic anemia, Cold AIHA, Paroxysmal Cold hemoglobinuria, Allo-immune Hemolytic anemia, immune Thrombocytopenic purpura, Evan's syndrome, IMMUNE HEMOLYTIC ANEMIA, Antibody-mediated hemolysis, AUTOIMMUNE HEMOLYTIC ANEMIA, Red cell destruction, cold AIHA syndrome, warm AIHA, ALLOIMMUNE HEMOLYTIC ANEMIA, DRUG-INDUCED HEMOLYTIC ANEMIA, ACQUIRED NON-IMMUNE HEMOLYTIC ANEMIA, INTRAVASCULAR HEMOLYSIS, BLACK WATER FEVER, HEMOPHAGOCYTIC SYNDROME, FRAGMENTATION HEMOLYSIS, MECHANICAL HEMOLYTIC ANEMIA, RED CELL FRAGMENTATION SYNDROME, MICROANGIOPATHIC HEMOLYTIC ANEMIA, HEMOLYTIC UREMIC SYNDROME, THROMBOTIC THROMBOCYTOPENIC PURPURA

Topics: Body Fluid, Blood Physiology, plasma, red blood cells, Erythropoiesis, Proerythroblast, Basophil erythroblast, Polychromatophil Erythroblast, Reticulocyte, Matured Erythrocyte, Hemoglobin, anemia, Hemorrhagic Anemia, Hemolytic Anemia, Thalassemia, Nutrition Deficiency Anemia, Pernicious anemia, Megaloblastic anemia, Aplastic Anemia, Idiopathic Anemia, Polycythemia, white blood cells, Neutrophils, Eosinophils, basophils, immunity, antibodies, antigens, Antigen-Presenting Cells, Passive Immunity, Passive Natural Immunization, hypersensitivity, allergy, blood groups, hemostasis, Platelets

Topics: Autoimmune diseases, Warm type Autoimmune, Cold type Autoimmune, immune Hemolytic anaemia, autoimmune haemolysis, extravascular haemolysis, cold Autoimmune Hemolytic anaemia, intravascular haemolysis, cold antibody Autoimmune Hemolytic anaemia, cold haemagglutin disease, paroxysmal cold haemoglobinuria, alloimmune Hemolytic anaemia

Topics: Clinical Immunology, immune system, innate immune responses, adaptive immune responses, Phagocytosis, natural killer cells, Eosinophils, antigen presenting cell, antigen presenting molecules, Monoclonal Antibodies, clinical trials, Xenotransplantation, cytokines, Cells of Adaptive Immunity, B-lymphocyte Antigen-specific Receptor, B-cell Differentiation, T-lymphocyte Antigen-specific Receptor, bone marrow, Antigen Dependent B-cell Differentiation, T Lymphocytes, inflammation, Vasodilatation, Increased Vascular Permeability, Edema, host defense, immunization, passive immunization, vaccines, vaccine technology, Hypersensitivity Reactions, Immediate Hypersensitivity Reactions, Antibody-mediated Hypersensitivity Reactions, Immune-complex Mediated Hypersensitivity, Cell-mediated Hypersensitivity, autoimmunity, Immunotherapy, Autoimmune Disorders, autoreactive antibodies, Immunodeficiency Disorders, Tumor Immunology, tumor antigens, Tumor Immunosurveillance, transplantation, Graft Rejection

Topics: Medical Physiology, Cell Signaling, Membrane Transport, Membrane Potential, Physiologic Regulation, plasma membrane structure, Solute Transport Mechanisms, Resting Membrane Potential, cellular signaling, neuromuscular physiology, nervous function, nervous system, action potential synaptic transmission, neurotransmission, Sensory Physiology, sensory system, somatosensory system, visual system, auditory system, vestibular system, Gustatory Systems, Olfactory Systems, motor system, autonomic nervous system, Parasympathetic Nervous System, Sympathetic Nervous System, Autonomic Integration, Hypothalamus, Brain Electrical Activity, Higher Cognitive Skills, Skeletal Smooth Muscle, Smooth Muscle, Motor Neurons, Excitation, Skeletal Muscle Metabolism, Skeletal Muscle Contraction, Muscle Plasticity, Epigenetics, Endocrine Muscle, Smooth Muscle, blood immunology, blood composition, blood function, Red Blood Cells, White Blood Cells, Platelet Formation, Blood Cell Formation, Blood Clotting, Immunology, Organ Interaction, Homeostasis, Immune System Activation, Immune Detection System, Immune System Defenses, Acute Inflammation, Chronic Inflammation, Anti-inflammatory Drugs, Organ Transplantation, Immunology, Immunologic Disorders, Neuroendoimmunology, cardiovascular physiology, Hemodynamics, Cardiac Muscle Mechanics, Cardiac Pump, Cardiac Cycle, Cardiac Excitation–Contraction Coupling, Cardiac Performance, Cardiac Output, Systemic Circulation, Arterial Pressure Measurement, Central Blood Volume, Microcirculation, Lymphatic System, Coronary Circulation, Cerebral Circulation, Hepatic Circulation, Skeletal Muscle Circulation, Cutaneous Circulation, Fetal Circulation, Placental Circulation, Circulatory Shock, respiratory physiology, ventilation, Spirometry, Lung Volumes, Minute Ventilation, Airway Resistance, Gas Transfer, Diffusing Capacity, Pulmonary Circulation, Ventilation, body fluids, Kidney Function, nephron, Renal Blood Flow, Glomerular Filtration, Glomerular Hemodynamic Forces, Tubular Reabsorption, Tubule Secretion, Urinary Concentration Mechanisms, Electrolyte Balance, fluid balance, Acid–Base Homeostasis, gastrointestinal physiology, Salivary Secretion, Gastric Secretion, Pancreatic Secretion, Biliary Secretion, Intestinal Secretion, Carbohydrate Digestion, Carbohydrate Absorption, Water Absorption, Electrolyte Absorption, Mineral Absorption, Vitamin Absorption, Liver Functions, Immune Surveillance, Gastrointestinal Regulation, temperature regulation, exercise physiology, Heat Dissipation, Thermoregulatory Control, Heat Acclimatization, endocrine physiology, Endocrine Control Mechanisms, Hypothalamus, Pituitary Gland, Thyroid Gland, Thyroid Hormone Synthesis, Adrenal Gland, Adrenal Medulla Catecholamines, Endocrine Pancreas, Islets of Langerhans, Islet Hormone Synthesis, Insulin, Glucagon Action, Diabetes Mellitus, Plasma Calcium, Phosphate Regulation, Bone Dysfunction, reproductive physiology, Male Reproductive System, Testicular Function

Topics: HUMAN BLOOD GROUPS, BLOOD GROUP, BLOOD GENOTYPE, BLOOD PHENOTYPE, Antigens, Antibodies, Blood group antibodies, Naturally occurring antibodies, Cold antibodies, warm antibodies, IgM antibodies, IgG antibodies, ANTIBODY IMMUNE RESPONSE, ABO SYSTEM, BOMBAY PHENOTYPE, H ANTIGEN, ABO antibodies, IMMUNE ABO ANTIBODIES, Rh Blood Group system, RH GENOTYPE, RhD positive, RhD negative, RhD antigen, WEAK D ANTIGEN, Partial D, D variants, RHESUS SYSTEM, Duffy antigen

Topics: Gene Transcription, Messenger RNA, DNA Mutation, gene expression, Lineage Commitment, Micro-RNAs, Regulatory Noncoding RNAs, DNA Replication, Telomeres, Cell Cycle, Apoptosis, Cellular Debris, Lysosomes, Protein Ubiquitination,  Clonal Hematologic Disorders, Erythropoiesis, Bone Marrow, Peripheral Blood, Hypochromic Microcytic Anemias, Iron Metabolism, Iron Absorption, Hepcidin, Iron Homeostasis, Iron‐Deficiency Anemia, Hypochromic Anemias, Sideroblastic Anemia, Lead Poisoning, alchohol, Lead Poisoning, Hematopoiesis, Hematopoietic Niche, growth factor signaling, Congenital Erythropoietic Porphyria, Congenital Erythropoietic Protoporphyria, iron overload, porphyrias, megoblastic anemia, Bone Marrow Appearances, Phagocytic Function, Leukocytosis, Leukoerythroblastic Reaction, Neutropenia, Myelokathexis, Lysosomal Storage Diseases, Hereditary Hemolytic Anemia, Hemolytic Anemia, Acquired Hemolytic Anemia, genetic disorders, Thalassemia, α‐Thalassemia, T Cells, B cells, Natural Killer Cells, Lymphocyte Proliferation, Somatic Hypermutation, Lymphocyte Circulation, Lymphocytosis, Lymphadenopathy, Primary Immunodeficiency Disorders, Granulopoiesis, Monocyte Production, Neutrophils, Polymorphs, Mononuclear Phagocytic System, Reticuloendothelial System, Autoimmune Lymphoproliferative Syndrome, Acquired Immunodeficiency Syndrome, Aplastic Anemia, Red Cell Aplasia, Congenital Dyserythropoietic Anemias, MYELODYSPLASTIC SYNDROMES, molecular genetics, Mirage Syndrome, Clonal Hematopoiesis, HEMATOLOGIC NEOPLASMS, MYELOID LEUKEMIA, Acute Myeloid Leukemia, MYELOPROLIFERATIVE NEOPLASMS, Chronic Myeloid Leukemia, Chronic Neutrophilic Leukemia, Nonleukemic Myeloproliferative Diseases, Polycythemia Vera, Myelofibrosis, Chronic Eosinophilic Leukemia, Myeloproliferative Disorder, ACUTE LYMPHOBLASTIC LEUKEMIA, Mastocytosis, Paraneoplastic Pemphigus, Myeloid Neoplasm, Lymphoid Neoplasm, Myelodysplastic Neoplasm, Myeloproliferative Neoplasm, Ring Sideroblast, Thrombocytosis, Juvenile Myelomonocytic Leukemia, CHRONIC LYMPHOCYTIC LEUKEMIA, Mature B‐Cell Leukemia, Mature T‐C

Topics: NORMAL IMMUNE RESPONSE, Innate Immunity, Adaptive Immunity, Lymphocytes, Macrophages, T lymphocytes, dendritic cells, Natural Killer Cells, Immunologic Memory, HYPERSENSITIVITY REACTIONS, IMMEDIATE HYPERSENSITIVITY, antibody-dependent cellular cytotoxicity, Antibody mediated cellular dysfunction, IMMUNE COMPLEX MEDIATED HYPERSENSITIVITY, T-Cell Mediated Delayed Type Hypersensitivity, T-CELL MEDIATED HYPERSENSITIVITY, T-Cell Mediated Cytotoxicity

Topics: Bilirubin Metabolism, Fetal Bilirubin Metabolism, Jaundice, bilirubin excretion, Antibody mediated haemolysis, Red Cell, Red Cell Enzyme defects, Red Cell Membrane defects, ABO Incompatibility, Rh Incompatibility, anti-E & c, anti- Kell, Minor blood group incompatibility, G-6-P-D deficiency, Pyruvate kinase deficiency, Hereditary spherocytosis, Elliptocytosis, EXTRAVASCULAR BLOOD, DRUG INDUCED HEMOLYSIS, Vitamin K3 induced haemolysis, POLYCYTHAEMIA, glucoronosyl transferase, Galactosaemia, Exchange Blood Transfusion, Phototherapy, Chronic Postkernicteric Encephalopathy, Bilirubin Encephalopathy, Bilirubin Toxicity, Encephalopathy, Breast Milk Jaundice, G6PD Deficiency, Iso-immune Haemolytic Diseases

Topics: IMMUNE HAEMOLYTIC ANAEMIAS, AUTO IMMUNE HAEMOLYTIC ANAEMIAS, immunoglobulin, Red cell destructionComplement mediated destruction, cold AUTO IMMUNE HAEMOLYTIC ANAEMIA, PAROXYMAL COLD HAEMOGLOBINURIA, ALLO IMMUNE HAEMOLYTIC ANAEMIA, DRUG INDUCED HAEMOLYTIC ANAEMIA, RED CELL FRAGMENTATION SYNDROME, MACRO ANGIOPATHIC HAEMOLYTIC ANAEMIA, MICRO ANGIOPATHIC HAEMOLYTIC ANAEMIAS, MARCH HAEMOGLOBINURIA, PAROXYSMAL NOCTURNAL HAEMOGLOBINURA, glycosylphosphatidylinositol

Topics: Haemopoiesis, anaemia, Erythropoiesis, Hypochromic anaemia, iron oveload, Megaloblastic anaemia, macrocytic anaemia, Haemolytic anaemia, granulocytes, monocytes, lymphocytes, spleen, haematological malignancy, Acute myeloid leukaemia, Chronic myeloid leukaemia, Myeloproliferative disease, myeloid leukaemia, Myelodysplasia, chronic lymphoid leukaemia, Hodgkin lymphoma, Non-Hodgkin lymphoma, Multiple myeloma, Aplastic anaemia, bone marrow failure, Stem cell transplantation, Platelets, blood coagulation, haemostasis, Bleeding disorders, platelet abnormalities, vascular abnormalities, Coagulation disorders, Thrombosis, Blood transfusion, Pregnancy haematology, neonatal haematology

Topics: thrombocytes, thrombosis, megakaryocytes, hematocytoblast, megakaryocyte, phospholipids

Topics: Transient erythoblastopenia, Aplastic anaemia, MEGALOBLASTIC ANAEMIA, IRON DEFICIENCY ANAEMIA, MICROCYTIC ANAEMIA, HAEMOLYTIC ANAEMIA, blood, blood products, RED CELL CONCENTRATE, LEUCOCYTE REDUCED CELLS, DEPLETED RED CELLS, WASHED RED CELLS, red cell synthesis, Recombinat human erythropoietin, Haematinics

Topics: Chemical barriers, Epithelial Chemical Barriers, Respiratory Tract Mucosae, Internal Defenses, Phagocytosis, Natural Killer Cells, Inflammation, Inflammation Response, Toll-like Receptors, Inflammatory Response, edema, Phagocytic Mobilization, Interferon, Interferon Family, Complement Pathways, C-reactive Protein, Antibody Production, fever, Complete Antigen, antigen, Haptens, Antigenic Determinants, Adaptive Immune System, Antibody-mediated immunity, humoral immunity, Active Immunity, vaccine, Passive Immunity