Drug resistance by Peter Ekwueme PDF free download

Topics: Drug Sources, Drug Benefit Assessment, Congeneric Drugs, Drug Administration, Oral Dosage Forms, dermatological agents, drug distribution, Drug Action, membrance permeation, drug transporters, drug elimination, drug metabolism, enteroheptaic circulation, presystemic elimination, pharmacokinetics, druig concentration, accumulation, dose-response relationship, drug-receptor interaction, agonists-antagonists, enantioselectivity, G-protein-couples receptors, plasma concentration, adverse drug effects, drug allergy, cutaenous reactions, pregnancy, lactation, drug-independent effects, cutaneous reaction, placebo theraphy, systems pharmacology, sympathetic system, cathecholamine actions, sympathomimetics, indirect sympathomimetics, Parasympathetic Nervous System, Parasympathetic Functions, Cholinergic Synapse, Parasympathomimetics, Parasympatholytics, biogenic agents, dopamine, histamine, serotonin, amino acids, vasodilators, organic nitrates, calcium antagonists, Renin-Angiotensin-Aldosterone System, ACE Inhibitors, smooth muscle, cardiac Drugs, Cardiac Glycosides, antiarrhythmic drugs, antianemic agents, anemias, iron compounds, antithrombotic agents, thrombosis therapy, Vitamin K, Heparin, fibrinolytics, platelet aggregation, plasma volume expanders, hyperlipoproteinemias, lipid-lowering agents, diuretics, water reabsorption, vasopressin, water and electrolyte disorders, Gastrointestinal Tract, Hyperacidity, antidiarrheal agents, motor system, muscle relaxants, nociceptors, pain, analgesics, eicosanoids, antipyretic analgesics, local anesthetics, opioids, General Anesthesia and General Anesthetic Drugs.lnhalational Anesthetics, Injectable Anesthetics, Anxiolytics, benzodiazepines, depressive illness, manic state, schizophrenia, endocrine system, hypothalamic hormone, hypophyseal hormone, thyroid hormone therapy, hyperthroidism, antithyroid drugs, glucocorticoid therapy, androgen, anabolic steroid, antiandrogen, follicular growth, ovulation, antibacterial drugs, antifungal drugs, antiviral drugs, antiparasitic drugs, tropical diseases, anticancer drugs, immune modulators

Topics: Macrolide Resistance, CLARITHROMYCIN, AZITHROMYCIN

Topics: Pharmacogenomics, Pharmacoepidemiology, DRUG SPECIFICITY, receptor classification, drug concentration, drug effect, spare receptors, COMPETITIVE ANTAGONISM, Irreversible Competitive Antagonism, Partial Agonists, Constitutive Receptor Activation, Inverse Agonists, two-state receptor model, Biased Agonism, Allosteric Modulation, Chemical Antagonism, Pharmacokinetic Antagonism, Receptor–Response Linkage, Physiological Antagonism, Desensitisation, Tolerance, Altered Drug Metabolism, Binding Reaction, Drug–Receptor Interactions, Receptor mechanisms, Ion Channels, Enzymes, Receptor Proteins, Receptor Heterogeneity, Ligand-Gated Ion Channels, Gating Mechanism, G Protein–Coupled Receptors, Proteinase-Activated Receptors, G proteins, phospholipase C, inositol phosphate system, Inositol phosphates, intracellular calcium, Diacylglycerol, protein kinase, MAP kinase system, GPCR desensitisation, Biopharmaceuticals, Chemical Mediators, Presynaptic Modulation, Postsynaptic Modulation, Cholinergic transmission, Nicotinic Receptors, Acetylcholine, Muscarinic Agonists, Muscarinic Antagonists, Ganglion Stimulants, Ganglion-Blocking Drugs, Neuromuscular-Blocking Drugs, Non-Depolarising Blocking Agents, Depolarising Blocking Agents, Cholinesterase Reactivation, Noradrenergic transmission, Adrenoceptor Agonists, α-Adrenoceptor antagonists, 5-Hydroxytryptamine, migraine, Adenosine, purine, Histamine, local hormone, Eicosanoids, Prostanoids, Leukotrienes, Platelet-Activating Factor, Bradykinin, peptide, Neuropeptides, Cytokine, Interferon, Cannabinoids, Endocannabinoids, Nitric oxide, Ischaemic Heart Disease, Antidysrhythmic Drugs, Myocardial Contraction, Anti-Anginal Drugs, Organic Nitrates, Calcium Antagonists, Endothelin, Vasoactive Drugs, Vasodilator Drugs, heart failure, Atherosclerosis, lipoprotein metabolism, Lipoprotein Transport, Lipid-Lowering Drugs, Fibrates, Haemostasis and thrombosis, Blood Coagulation, Warfarin, Platelet Adhesion, Platelet Activation, Antiplatelet Drugs, Adenosine Receptor Antagonists, Fibrinolysis, Thrombolysis, Fibrinolytic Drugs

Topics: Catalyst, COENZYMES, Metal activated enzymes, Metalloenzymes, Active Site, Catalytic site, Binding Site, Enzyme inhibition, RATE OF ENZYME ACTIVITY, ENZYME KINETICS, Michaelis–Menten Equation

Topics: Drug-nutrient interaction, Food-drug interaction, Pharmacokinetics, Pharmacodynamics, Absorption, ISONIAZID, PHENELZINE, GLUCOSE-6-PHOSPHATE DEHYDROGENASE ENZYME DEFICIENCY, Warfarin, Drug Induced Nutritional Deficiencies

Topics: antimicrobial resistance, antiparasitic resistance, penicillins, tetracycline, cephalosporin, amphotericin B, Aminoglycosides, antifungal drugs, azole compounds, allyamines, Antimalarial resistance, Chloroquine resistance, Antifolate resistance, Artemisinin resistance, ANTIPARASITIC DRUG RESISTANCE, Trichomoniasis, Trichomonas resistance, Leishmaniasis, African trypanosomiasis, Trypanosomiasis drug resistance

Topics: drug administration, pharmacokinetics, membrane trnasport, distribution of drugs, kinetics of elimination, receptor pharmacology, drug development, clinical pharmacology, adverse drug effects, autonomic nervous system, cholinergic transmission, cholinergic drugs, anticholinergic drugs, autonomic ganglia, adrenergic transmission, adrenergic drugs, antiadrenergic drugs, adrenergic receptor antagonists, glaucoma, autacoids, histamine, antihistaminics, 5-hydroxytryptamine, migraine, prostaglandins, leukotrienes, eicosanoids, platelet activating factor, nonsteroidal antiinflammatory drugs, antipyretic-analgesics, antirheumatoid drugs, antigout drugs, respiratory system drugs, cough, bronchial asthma, hormones, anterior pituitary hormones, thyroid hormones, thyroid inhibitors, insulin, oral antidiabetic drugs, glucagon, corticosteroid, androgen, erectile dysfunction, estrogen, progestin, contraceptives, oxytocin, calcium balance, skeletal muscle relaxants, peripheral nervous system, somatic nervous system, local anaesthetics, central nervous system, general anaesthetics, ethyl, methyl, sedative-hypnotics, antiepileptic drugs, antiparkinsonian drugs, mental illness, antipsychotic, antimanic, antidepressant, antianxiety, Opioid analgesiscs, antagonists, CNS stimulants, cognition enhancers, cardiovascular drugs, cardiac electrophysiological considerations, renin-angiotensin system, nitric oxide, vasoactive peptide signal molecules, cardiac glycoside, heart failure, antiarrhythmic drugs, antianginal drugs, anti-ischaemic drugs, antihypertensive drugs, diuretics, urine formation, antidiuretics, blood formation, haematinics, erythropoietin, hypolipidaemic drugs, peptic ulcer, gastroesophageal reflux disease, antiemetic drugs, prokinetic drugs, digestant drugs, constipation, diarrhoea, antimicrobial drugs, sulfonamides, beta-lactam antibiotics, tetracycline, chloramphenicol, broad spectrum antibiotics, aminoglycoside antibiotics, macrolide, lincosamide, glycopeptide, antibacterial antibiotics, urinary antiseptics, antitubercular, antileprotic drugs, antifungal, antiviral, anticancer

Topics: drug dependence, psychoactive drug, psychotropic substance, CNS stimulants, xanthine, cocaine, Ephedrine, Benzodiazepines, sedatives, hallucinogens, KETAMINE, PHENCYCLIDINE, cannabinoids, Recreational drugs, inhalant

Topics: adverse drug reactions, pharmacovigilance

Topics: Pharmaceutic interaction, Pharmacodynamic interaction, Pharmacokinetic interaction, SYNERGISM, ANTAGONISM, PLASMA PROTEINS, Plasma albumin, DRUG FOOD INTERACTION, DRUG DISEASE INTERACTION

Topics: Drug Therapy, Pharmacokinetics, Drug–Receptor Interactions, Pharmacodynamics, Autonomic Nervous System, Cholinergic Agonists, Cholinergic Antagonists, Adrenergic Agonists, Adrenergic Antagonists, Neurodegenerative Diseases, Anxiolytic drugs, Hypnotic Drugs, Antidepressants, Antipsychotic Drugs, Anesthetics, Opioids, CNS Stimulants, Antihypertensives, diuretics, Heart Failure, epilepsy, Antiarrhythmics, Antianginal Drugs, Anticoagulants, Antiplatelet Agents, Hyperlipidemia, Endocrine System, Pituitary, Thyroid, diabetes, estrogen, androgen, adrenal hormone, bone metabolism, Chemotherapeutic Drugs, Antimicrobial Therapy, Cell Wall Inhibitors, Protein Synthesis Inhibitors, Quinolones, Folic Acid Antagonists, Urinary Tract Antiseptics, Antimycobacterial Drugs, Antifungal Drugs, Antiviral Drugs, Anticancer Drugs, Immunosuppressants, Histamine, Serotonin, Anti-inflammatory Agents, Antipyretic Agents, Analgesic Agents, Gastrointestinal drugs, Antiemetic Drugs, Urologic Disorders, anemia, Dermatologic Disorders, Clinical Toxicology, drugs of abuse, Antiprotozoal Drugs, Anthelmintic Drugs

Topics: Eukaryotic cell, cell, Carbohydrates, Monosaccharides, glucose, Disaccharides, Polysaccharides, Homopolysaccharides, Heteropolysaccharides, Agar, pectin, Glycoproteins, Lipids, Fatty acids, Essential fatty acids.Phospholipids, Glycolipids, Lipoproteins, Steroids, Amphipathic lipids, Soaps, detergents, Proteins, Amino Acids, Nucleic Acids, Nucleotides, Enzymes, DNA, RNA, enzyme activity, Active site, Enzyme inhibition, Enzyme specificity, Coenzymes, enzyme action, Non-protein enzymes, Isoenzymes, Vitamins, Vitamin A, Vitamin D, Vitamin E, Vitamin K, Vitamin C, Ascorbic acid, Thiamine, Vitamin B1, Riboflavin, Vitamin B2, Niacin, Pyridoxine, Vitamin B6, Biotin, Pantothenic acid, Folic acid, Cobalamin, Vitamin B12, Choline, Inositol, Lipoic acid, Para aminobenzoic acid, Bioflavonoids, Antivitamins, Physiological Biochemistry, Digestion, Absorption, Plasma Proteins, Albumin, Globulins, Immunoglobulins, Blood clotting, Hemoglobin, Porphyrins, Hemoglobin derivatives, Abnormal hemoglobins, Sickle-cell anemia, sickle-cell hemoglobin, Thalassemias, Porphyrias, Jaundice, Biological Oxidation, Bioenergetics, High-energy compounds, Electron transport chain, Oxidative phosphorylation, Metabolism, Glycolysis, Citric acid cycle, Gluconeogenesis, Glycogen metabolism, Glycogen storage diseases, Hexose monophosphate shunt, Uronic acid pathway, Glyoxylate cycle, Fatty acid oxidation, Ketone bodies, Fatty liver, obesity, Atherosclerosis, Alcohol metabolism, Amino acid pool, Urea cycle, Glycine, Phenylalanine, tyrosine, Tryptophan, Sulfur amino acids, One-carbon metabolism, Histidine, proline, arginine, Lysine, Glutamate, glutamine, Aspartate, asparagine, Serine, Threonine, Biogenic amines, Polyamines, purine, Mineral Metabolism, Nutrition, Hormones, Organ Function Tests, water, Tissue Proteins, Body Fluids, Molecular Biology, Biotechnology, DNA-Replication, Transcription, Translation, Gene Expression, Recombinant DNA, Human Genome Project, Gene Therapy, Bioinformatics, Xenobiotics, Detoxification, Prostaglandins, Free Radicals, Antioxidants, Environmental Biochemistry, Insulin, cancer, Acquired Immunodeficiency Syndrome

Topics: Biochemistry, Organic Chemistry, functional groups, polymeric compounds, isomerism, amino acids, peptides, proteins, Enzymes, Biocatalysis, Chemical Equilibria, Chemical Energetics, catalysts, enzymes, energetic coupling, energy-rich compounds, enzyme catalysis, Michaelis theory, Coenzymes, prosthetic groups, Oxidoreductases coenzymes, Group-Transferring Coenzymes, nucleic acids, protein biosynthesis, bases nucleosides, nucleotides, deoxyribonucleic Acid, DNA biosynthesis, RNA synthesis, protein biosynthesis, virus biochemistry, Nucleic Acid-Cleaving Enzymes, Phosphatases, protein metabolism, proteolytic enzymes, Endopeptidases, Exopeptidases, Dipeptidases, Amino Acids, Decarboxylation, transamination, Oxidative Deamination, urea cycle, Porphyrins, Hemins, Porphyrin Catalysis blood pigment degradation, Cytochromes, Catalases, Peroxidases, Chlorophyll, biologic Oxidation, oxygen metabolism, Combustion, Biologic Oxidation, redox potential respiratory chain, Electron-Transport Particles, Oxidative Phosphorylation, Respiratory Chain Phosphorylation, Oxygen-Activating Enzymes, citrate cycle, Glyoxylate Cycle, fat metabolism, fats, fatty acids, Phosphatides, Cerebrosides, Gangliosides, Glycerophosphatides, Sphingolipids, cholesterol biosynthesis, sterols, plant steroids, vitamin D, bile acids, stroid hormones, carotenoids, Vitamin A, Tocopherol, Phylloquinone, Ubiquinone, Plastoquinone, Simple Sugars, Monosaccharides, Glucose Oxidation, Glycolysis, Alcoholic Fermentation, fructose metabolism, Aerobic Carbohydrate Breakdown, photosynthesis, Photophosphorylation, water photolysis, Glycosides, Oligosaccharides, Polysaccharides, glycoside bond, disaccharides, Polysaccharides, Homoglycans, Mucopolysaccharides, Carbohydrates Metabolism, fatty acids metabolism, protein metabolism, Endoplasmic Reticulum, cell, Mitochondria, cytoplasm, hormones, hormonal regulation, Adrenocortical Hormones, Gonadal Hormones, Thyroid Hormones, Parathyroid Hormone, Pancreatic Hormones, Hypophyseal Hormones, Tissue Hormones, Pheromones, mineral metabolism, water balance, active transport, Acid-Base Equilibrium, nutrition, vitamins, caloric value, Essential Food Components, Fat-Soluble Vitamins, Water-Soluble Vitamins, digestive tract, liver, blood kidney, urine, Excretion Products, Muscle biochemistry, Nerve Conduction biochemistry

Topics: Pharmaceutical microbiology, bacteria, fungi, viruses, protozoa, pathogen, host responses, microbial biofilms, immunology, vaccination, immunization, prescribing therapeutics, Antibiotics, synthetic antimicrobial agents, Public health microbiology, Antibiotic prescribing, antibiotic stewardship, Contamination, infection control, Microbial spoilage, infection risk, contamination control, Chemical disinfectants, antiseptics, Non-antibiotic antimicrobial agents, Sterilization procedures, sterility assurance, Pharmaceutical production, Sterile pharmaceutical products, Recombinant DNA technology

Topics: drug action, drug absoprtion, drug distribution, drug biotransformation, microsomal enzymes, drug excretion, prolongation of drug action, drug intolerance, drug hypersensitivity, chemical transmitters, 1-Acetylcholine, muscarinic receptors, nicotinic receptors, 2-Noradrenaline, Norepinephrine, Catecholamines, sympathetic depressants

Topics: Pharmacokinetics, Pharmacodynamics, Life Cycle of a Drug, Slow Absorption, Faster Absorption, Bioavailability, Depot Binding, Degradation, Excretion, Drug Effectiveness, Dose-response curve, Therapeutic Index, Effective dose, Lethal dose, Effective concentration, Drug Efficacy, Drug potency, Drug-drug Interactions, Cumulative Effects, Additive Effects, Synergistic Effects, Antagonistic Effects, Agonism, Antagonism, drug-receptor interaction

Topics: antibiotic, antimicrobial drugs, Chemotherapeutic drug resistance, Antimicrobial drug Selection, Antimicrobial drug Selection, Antimicrobial drug treatment, Antimicrobial Therapy

Topics: Hormone Synthesis, Thyroid Hormone, Binding Proteins, Thyroxine Binding Globulin, Thyroxine-Binding Prealbumin, Thyroid Axis Regulation, Thyrotoxicosis, Grave’s Disease, Pretibial myxedema, Thyroid acropachy, Radioiodine Therapy, Thyrotoxic Crisis, Thyroid Storm, hypothyroidism, Myxedema coma

Topics: quinolones, Fluoroquinolone, First Generation Quinolone, Second Generation Quinolone, Third Generation Quinolone, Fourth Generation Quinolone, bacteria, Antibiotic Misuse, Antibiotic resistance

Topics: Enzymes, Enzyme kinetics, Basic concept of enzymes, Classification of enzymes, Nature of enzymes, enzyme action, enzyme-catalyzed reaction, Michaelis - Menten equation