Topics: Pharmacogenomics, Pharmacoepidemiology, DRUG SPECIFICITY, receptor classification, drug concentration, drug effect, spare receptors, COMPETITIVE ANTAGONISM, Irreversible Competitive Antagonism, Partial Agonists, Constitutive Receptor Activation, Inverse Agonists, two-state receptor model, Biased Agonism, Allosteric Modulation, Chemical Antagonism, Pharmacokinetic Antagonism, Receptor–Response Linkage, Physiological Antagonism, Desensitisation, Tolerance, Altered Drug Metabolism, Binding Reaction, Drug–Receptor Interactions, Receptor mechanisms, Ion Channels, Enzymes, Receptor Proteins, Receptor Heterogeneity, Ligand-Gated Ion Channels, Gating Mechanism, G Protein–Coupled Receptors, Proteinase-Activated Receptors, G proteins, phospholipase C, inositol phosphate system, Inositol phosphates, intracellular calcium, Diacylglycerol, protein kinase, MAP kinase system, GPCR desensitisation, Biopharmaceuticals, Chemical Mediators, Presynaptic Modulation, Postsynaptic Modulation, Cholinergic transmission, Nicotinic Receptors, Acetylcholine, Muscarinic Agonists, Muscarinic Antagonists, Ganglion Stimulants, Ganglion-Blocking Drugs, Neuromuscular-Blocking Drugs, Non-Depolarising Blocking Agents, Depolarising Blocking Agents, Cholinesterase Reactivation, Noradrenergic transmission, Adrenoceptor Agonists, α-Adrenoceptor antagonists, 5-Hydroxytryptamine, migraine, Adenosine, purine, Histamine, local hormone, Eicosanoids, Prostanoids, Leukotrienes, Platelet-Activating Factor, Bradykinin, peptide, Neuropeptides, Cytokine, Interferon, Cannabinoids, Endocannabinoids, Nitric oxide, Ischaemic Heart Disease, Antidysrhythmic Drugs, Myocardial Contraction, Anti-Anginal Drugs, Organic Nitrates, Calcium Antagonists, Endothelin, Vasoactive Drugs, Vasodilator Drugs, heart failure, Atherosclerosis, lipoprotein metabolism, Lipoprotein Transport, Lipid-Lowering Drugs, Fibrates, Haemostasis and thrombosis, Blood Coagulation, Warfarin, Platelet Adhesion, Platelet Activation, Antiplatelet Drugs, Adenosine Receptor Antagonists, Fibrinolysis, Thrombolysis, Fibrinolytic Drugs

Topics: Psychopharmacology, Drugs, brain, behavior, Nervous System, chemical signaling, Catecholamines, Neurotransmitter Synthesis, Neurotransmitter Receptors, Synaptic Plasticity, Catecholamine Synthesis, Dopaminergic System, Noradrenergic System, Serotonin, Serotonin Synthesis, Serotonergic System, Acetylcholine, Cholinergic System, Glutamate, drug abuse, drug addiction, alcohol, Alcohol Use Disorder, Opioids, Narcotic Analgesics, Opioid Receptors, Endogenous Neuropeptides, Psychomotor Stimulants, Cocaine, Amphetamine, Nicotine, Caffeine, cigarette smoking, vaping, Marijuana, Cannabinoids, Hallucinogens, Ketamine, Mescaline, Psilocybin, Inhalants, Anabolic–Androgenic Steroids, Anxiety Disorder, Affective Disorders, Antidepressants, Mood Stabilizers, Schizophrenia, Antipsychotic Drugs, Neurodegenerative Diseases, Parkinson’s Disease, Alzheimer’s Disease, Huntington’s Disease, Amyotrophic Lateral Sclerosis, Multiple Sclerosis

Topics: vomitting, nausea, Chemoreceptor trigger zone, Antiemetic Drugs, SEROTONIN ANTAGONISTS, 5-HT3 ANTAGONISTS, D2 RECEPTOR ANTAGONISTS, Prokinetic D2-receptor antagonists, Neuroleptic D2 receptor antagonists, antipsychotic receptor antagonists, NEUROKININ1 RECEPTOR ANTAGONISTS, H1-RECEPTOR ANTAGONISTS, MUSCARINIC RECEPTOR ANTAGONISTS, GLUCOCORTICOIDS, CANNABINOIDS

Topics: BULK PURGATIVES, OSMOTIC LAXATIVES, SALINE LAXATIVES, FAECAL SOFTENERS, EMOLLIENT LAXATIVES, SURFACTANTS, STIMULANT, IRRITANT PURGATIVES, LUBRICANT LAXATIVES, ANTI-EMETIC AGENTS, ANTI-NAUSEANTS, SEROTONIN 5-HT3 ANTAGONISTS, DOPAMINE-2 RECEPTOR ANTAGONISTS, H1 ANTIHISTAMINES, ANTICHOLINERGICS, NEUROKININ RECEPTOR ANTAGONISTS, PHENOTHIAZINES, BUTYROPHENONES, CORTICOSTEROIDS, CANNABINOIDS, BENZODIAZEPINES, MIGRAINE ATTACK, MIGRAINE HEADACHE, ANALGESICS, 5-HT1 AGONISTS, DOPAMINE ANTAGONISTS, ANTIEMETICS, PROKINETICS, ORGANIC NITRATES, NITRITES, CALCIUM CHANNEL BLOCKERS, BETA-ADRENOCEPTOR BLOCKERS, ANTIPLATELET DRUGS, PARTIAL FATTY ACID OXIDATION INHIBITORS, SINOATRIAL PACEMAKER CURRENT

Topics: Carcinogenesis, PHYTOCHEMICALS, ANTICANCER DRUGS, GINGEROL, LYCOPENE, FISETIN, GENISTEIN, APIGENIN, RESVERATROL, KAEMPFEROL, PODOPHYLLOTOXIN, CANNABINOIDS

Topics: drug dependence, psychoactive drug, psychotropic substance, CNS stimulants, xanthine, cocaine, Ephedrine, Benzodiazepines, sedatives, hallucinogens, KETAMINE, PHENCYCLIDINE, cannabinoids, Recreational drugs, inhalant